Vaccinations for Your Pets

Canine Vaccinations

The canine distemper vaccine is typically given in some variation of a combination vaccine that also protects your pet from several other serious diseases, such as parvovirus infection.  Many of the diseases that are prevented by this combination vaccine have no effective treatment other than supportive care; however, vaccination can prevent these diseases or minimize the signs of illness. Other vaccines, such as the rabies and Bordetella vaccines, may be given in addition to the canine distemper/parvo combination vaccine.

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Canine Distemper Vaccinations and Rabies

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Canine Distemper/Parvo Vaccination

While commonly called canine distemper vaccination, this vaccine typically protects your pet against more than just distemper.  That’s because it is actually a combination of vaccines in one injection that will protect your pet from several serious diseases.  Canine distemper is considered a core vaccine. This means that, because canine distemper is a serious, highly contagious disease with a high death rate, organized veterinary medicine has determined that all dogs should be protected from this disease.  The exact combination of your dog’s distemper combination vaccine depends on your dog’s age and individual disease-risk profile, but in general, the most important diseases to protect against are canine distemper, canine adenovirus-2 infection (hepatitis and respiratory disease), canine parvovirus infection, and parainfluenza.  The abbreviation for this combination vaccine is frequently written as “DHPPV,” “DHPP,” “DA2PP,” or “DA2PPV” on your pet’s health records.  The letters in these abbreviations are defined as follows:

D = Canine distemper virus. Infection with this virus is serious, with a death rate approaching 50% in untreated dogs.  The virus attacks the respiratory, digestive, and brain/nervous systems of dogs.

H = Hepatitis. Since this vaccine protects against canine adenovirus-2 and adenovirus-1, it is often referred to as A2.  Canine adenovirus-1 causes canine infectious hepatitis, a serious disease that affects the liver.  Canine adenovirus-2 causes respiratory disease and is one of the infectious agents commonly associated with canine infectious tracheobronchitis, also known as kennel cough.

A2 = Canine adenovirus-2. This virus causes a respiratory disease in dogs (see above).

P = Parvovirus. Infection with this virus is highly contagious and serious, with a death rate approaching 90% in untreated dogs.  The virus attacks the digestive and immune systems of unvaccinated animals, causing debilitating diarrhea and vomiting.

P = Parainfluenza. This is a mild respiratory viral disease in dogs.

V = Virus.

Other Distemper Combination Vaccines

Depending on your dog’s individual disease risk, which includes your dog’s age (puppy, adult, or senior) and lifestyle (active and outdoors or primarily indoors), your pet’s combination vaccine may protect against additional diseases.  Some of these vaccines are considered non-core, meaning they are optional and only recommended for pets with certain exposure risks.  The “C” in “DA2PPV-C” and the “L” in “DA2PPV-L” are defined as follows:

C = Coronavirus. This causes a highly contagious viral disease in dogs.  The disease typically affects the intestinal tract of dogs, causing vomiting and diarrhea.  Vaccination against this virus is generally considered noncore (optional) but may be recommended in areas where coronavirus is very common.

L = Leptospirosis. This potentially serious bacterial disease attacks the kidneys and liver of infected dogs and can be transmitted to humans.  Vaccination against this disease is generally considered non-core but may be recommended in areas where leptospirosis is common.

Rabies

Rabies is a 100% fatal disease of mammals. Because there is no effective treatment and the disease can also infect humans, vaccination against the rabies virus is required by law in most states of the US and usually mandatory for travel between countries. Typically, the rabies vaccine is administered to pets in a separate injection at the same time as the canine distemper combination vaccine.  However, the rabies vaccine can also be given alone (at a separate visit) or at the same time as other vaccines (such as the Lyme disease vaccine).  Rabies is considered to be a core vaccine for dogs.  It is important to remember that vaccination is a medical procedure and you should follow your veterinarian’s instructions on how to monitor your pet for signs of a reaction.  Although rare, they can occur.

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Feline Vaccinations

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Deciding which vaccines your cat should receive requires that you have a complete understanding of the benefits and risks of the procedure.  For this reason, it is extremely important that you discuss vaccination with your veterinarian so he or she can help you decide which vaccines are most appropriate.  Be sure to inform your veterinarian of your cat’s lifestyle, environment, medical history, current medical problems, and medications your cat may be receiving.  Remember, your veterinarian is more than willing to answer any questions you may have and will help you make the right vaccine choices.

Why does my cat need to be vaccinated?

The immune system plays a pivotal role in maintaining your cat’s health.  One of the most important functions of this complex system of specialized cells and molecules is to protect cats from disease and infection caused by viruses, bacteria, and a host of other microbes and parasites.  Vaccines help prepare your cat’s immune system to fend off invasion by a particular disease-causing organism. Vaccines contain antigens, which to the immune system “look” like the organism but don’t, ideally, cause disease.  When a vaccine is administered, the immune system mounts a protective response. Then if your cat is subsequently exposed to the disease-causing organism, its immune system is prepared to either prevent infection or reduce the severity of disease.  Though vaccines play an important role in controlling infectious diseases, most do not induce complete protection from disease, nor do they induce the same degree of protection in all cats.  For extra protection, you should make every effort to reduce your cat’s exposure to infected cats or contaminated environments.

Why do kittens require a series of vaccinations?

During the first few hours after birth, kittens ingest maternal antibodies contained in their mother’s milk.  These antibodies help protect the kitten from infectious diseases until its own immune system is more mature.  Unfortunately, maternal antibody also interferes with a vaccine’s ability to stimulate the kitten’s immune system.  To counteract this problem, veterinarians often administer a series of vaccines, usually beginning when the kitten is around six to eight weeks of age.  Vaccination is then repeated at three- or four-week intervals until maternal antibody has waned, usually at around twelve weeks of age.  In some cases (e.g., rabies vaccines) the initial vaccine is not given until maternal antibody has disappeared altogether.

Does my adult cat need to be vaccinated every year?

The answer depends in part on the vaccine.  For example, certain feline rabies vaccines provide protection for longer than one year, so vaccination with a triennially approved rabies vaccine every three years (after the initial series is completed, and when consistent with local rabies vaccine requirements) is sufficient.  Recent research suggests that panleukopenia, rhinotracheitis, and calicivirus vaccines provide adequate protection for several years, so that many veterinarians are now recommending that this vaccine be boosted no more than once every three years.  Unfortunately, far less is known about the duration of protection provided by other vaccines.  Until that information is known, annual vaccination with those products-when their administration is necessary-is a good idea.

Are vaccines dangerous?

Not usually.  Unfortunately, a perfect, risk-free vaccine does not exist.  Vaccines are indispensable in fighting feline infectious disease.  But as with any medical procedure, there is a small chance that reactions may develop as a result of vaccination.  To maximize the benefits of vaccination while minimizing the risks, it is important to vaccinate only against infectious agents to which your cat has a realistic risk of exposure, infection, and subsequent development of disease.  Also, make sure to inform your veterinarian of any problems your cat is currently experiencing, medications your cat is receiving, or vaccine reactions experienced in the past before your cat is vaccinated again.  Reactions may be mild or (very rarely) severe.

Mild Reactions

The following reactions are fairly common and usually start within hours to several days after vaccination.  They typically last no more than a few days.

  • discomfort at the site where the vaccine was given
  • mild fever
  • diminished appetite and activity
  • sneezing about four to seven days after administration of an intranasal vaccine
  • temporarily sore joints and lameness following calicivirus vaccination
  • Development of a small, firm, painless swelling under the skin at the site where the vaccine was given. The swelling usually goes away after several weeks, but if you notice such a swelling, contact your veterinarian.
  • Lameness, loss of appetite, and fever beginning approximately one to three weeks after Chlamydia psittaci vaccination.

Serious Reactions

These reactions occur very rarely:

  • a serious and potentially life-threatening allergic reaction within several minutes to an hour after vaccination

What should I do if I think my cat is having a reaction to a vaccine?

Even though vaccine-related disease is uncommon, the consequences can be serious.  Your veterinarian is the person most qualified to advise you if adverse side effects occur.

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What vaccines are currently available for my cat?

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Panleukopenia: Feline panleukopenia (also called feline distemper) is a highly contagious and deadly viral disease.  Signs include extreme listlessness and loss of appetite.  Fever, vomiting, and diarrhea are frequently seen, but some cats die suddenly with few clinical signs.  A high percentage of cats with panleukopenia-especially kittens-die from the infection.  Feline panleukopenia virus is shed in the feces of an infected cat and can survive extremes of temperature and humidity for months to years. The virus is resistant to most available disinfectants.  Until recent years panleukopenia was the most serious infectious disease of cats, killing thousands every year.  Thanks to the highly effective vaccines currently available, panleukopenia is now considered an uncommon disease.  Immunity induced by panleukopenia vaccines is excellent, and most vaccinated cats are completely protected from infection and disease.  Vaccination is recommended for all cats.

Feline Herpesvirus and Feline Calicivirus: Feline herpesvirus (the cause of feline viral rhinotracheitis) and feline calicivirus are estimated to be responsible for 80-90 percent of infectious feline upper respiratory tract diseases.  Although usually not serious in adult cats, disease caused by these viruses may be severe-and sometimes fatal-in kittens.  Sneezing, runny eyes, runny nose, and fever are the most typical signs of infection.  In addition to upper respiratory tract disease, lameness and chronic oral inflammatory disease have been linked to calicivirus infection.  Both viruses are shed in secretions from the nose, eyes, and mouth of infected cats.  Cats become infected by direct exposure to infected individuals, either from sneezed droplets, or from contaminated objects such as food and water dishes. Most cats are exposed to either or both of these viruses at some time during their lives, usually during kittenhood.  Once infected, many cats never completely rid themselves of viruses.  These carrier cats shed viruses either continuously or intermittently for long periods of time-perhaps for life-and serve as a major source of infection to other cats.  Protection induced by the currently available vaccines minimizes the severity of disease, but does not prevent disease in all cats.  Nonetheless, vaccination is recommended for all cats.

Rabies: Rabies is an increasing threat to cats. At present, the number of reported feline rabies cases in the United States far exceeds that of dogs and all other domestic animals. Rabies is routinely fatal and is a major public health concern. Because of the potential for human exposure, rabies vaccination is recommended for all cats and is required by law in many parts of the country.

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Feline Leukemia Virus: Feline leukemia virus (FeLV) is the leading viral killer of cats. The virus is spread in the saliva and nasal secretions of infected cats; infection is transmitted through prolonged contact with infected cats, bite wounds, and from an infected mother cat to her kittens. Disease caused by FeLV is very serious, and it is estimated that fewer than 20 percent of infected cats will survive more than three years after being infected. Anemia (a deficiency of oxygen-carrying red blood cells), cancer, and secondary infections resulting from immune deficiency are the most common consequences of infection. Outdoor cats, indoor/outdoor cats, and cats exposed to such individuals are at greatest risk of exposure to FeLV. Cats living in households with FeLV-infected cats or with cats of unknown infection status are also at risk. Kittens younger than 4 months of age appear to be much more susceptible to infection than are adult cats. Indoor-only adult cats with little chance of exposure to potentially infected cats are not likely to be exposed or infected. Vaccination against FeLV is recommended for cats at risk of exposure, especially those younger than four months of age. Vaccination is not recommended for cats with minimal to no risk of exposure, especially those older than four months of age. Because FeLV vaccines do not induce protection in all cats, avoiding exposure to infected cats remains the single best way to prevent your cat from becoming infected.

Feline Infectious Peritonitis: Feline infectious peritonitis (FIP) results from infection with feline coronavirus. Many different strains of the virus can infect cats, but most do not produce serious disease: usually less than 1 to 5 percent of coronavirus-infected cats develop FIP. Coronaviruses are shed primarily in the feces of infected cats. Most cats become infected by ingesting the virus, either as a result of direct contact with an infected cat or by exposure to virus-contaminated surfaces such as litter boxes, feeding bowls, bedding, clothing, or toys. A high percentage of cats residing in multiple-cat environments are exposed and ultimately infected with feline coronavirus, but exposure is far less common in households with fewer cats. Even though cats of all ages can develop the disease, most of those that develop FIP are younger than two years. Individuals with FIP rarely survive regardless of treatment. A vaccine to prevent FIP is available, but considerable controversy surrounds its ability to prevent disease.

Feline Immunodeficiency Virus: Feline immunodeficiency virus (FIV) is another viral killer of cats. The primary mode of virus spread is through bite wounds, so cats that get outdoors and fight are at greatest risk of infection.  Cats in households with stable social structures where housemates get along well are at little risk.  Infected cats may appear normal for years.  However, infection eventually leads to a state of immune deficiency that hinders the cat’s ability to protect itself against other infections. The same bacteria, viruses, protozoa, and fungi that may be found in the everyday environment – where they usually do not affect healthy animals – are responsible for many of the diseases associated with FIV.  Keeping cats indoors and away from potentially infected cats that might bite them markedly reduces their likelihood of contracting FIV infection.  Vaccines to help protect against FIV infection are available.  Not all vaccinated cats will be protected, so preventing exposure will remain important even for vaccinated pets. In addition, vaccination may have an impact on future FIV test results.  It is important that you discuss the advantages and disadvantages of vaccination with your veterinarian to help you decide whether FIV vaccines should be administered to your cat.

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What vaccines should cats receive?

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The decision depends on the following factors:

  • Your cat’s risk of exposure to the disease-causing organism, in part dependent on the health of other cats to which yours is exposed, and the environment in which your cat lives.
  • The consequences of infection
  • The age and health of your cat
  • The protective ability of the vaccine
  • The frequency or severity of reactions associated with vaccination
  • The risk an infected cat poses to human health (e.g., rabies virus)
  • Vaccine reactions your cat may have experienced in the past
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